Prostaglandins, related compounds, and the perinatal pulmonary circulation

Clin Perinatol. 1984 Oct;11(3):565-79.

Abstract

It is clear that prostaglandins and related compounds are important in the physiology and pathophysiology of the perinatal pulmonary circulation. This article focuses on what is known about prostaglandin-related compounds (PRC) in the pulmonary circulation of the developing and newly born mammal. Also included is a discussion of the effects of PRC on the ductus arteriosus and on the systemic circulation.

Publication types

  • Review

MeSH terms

  • Animals
  • Animals, Newborn
  • Arachidonic Acids / metabolism
  • Arachidonic Acids / pharmacology
  • Blood Pressure / drug effects
  • Epoprostenol / pharmacology
  • Female
  • Fetus / physiology*
  • Humans
  • Hydroxyeicosatetraenoic Acids / pharmacology
  • Hypertension, Pulmonary / physiopathology
  • Infant, Newborn*
  • Lung / blood supply
  • Persistent Fetal Circulation Syndrome / physiopathology
  • Pregnancy
  • Prostaglandin Antagonists / pharmacology
  • Prostaglandin D2
  • Prostaglandins / metabolism
  • Prostaglandins / physiology*
  • Prostaglandins D / pharmacology
  • Prostaglandins E / pharmacology
  • Prostaglandins F / pharmacology
  • Pulmonary Circulation* / drug effects
  • SRS-A / pharmacology
  • SRS-A / physiology
  • Sheep
  • Thromboxanes / physiology
  • Vascular Resistance
  • Vasoconstriction

Substances

  • Arachidonic Acids
  • Hydroxyeicosatetraenoic Acids
  • Prostaglandin Antagonists
  • Prostaglandins
  • Prostaglandins D
  • Prostaglandins E
  • Prostaglandins F
  • SRS-A
  • Thromboxanes
  • Epoprostenol
  • Prostaglandin D2