Gene conversion at different points in the mitotic cycle of Saccharomyces cerevisiae

Mol Gen Genet. 1984;195(1-2):139-43. doi: 10.1007/BF00332736.


In the Saccharomyces cerevisiae mitotic cycle, the timing of radiation-induced gene conversion has been studied using thermosensitive cell division cycle mutants. The cells were found to perform conversion at different G1 or post-replication steps. A lower yield in induction is found during the G2 phase and is explained by the competition for recombinational repair between sister chromatids and homologous chromosomes. The results are discussed in relation to repair.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Alleles
  • Cell Cycle
  • Crosses, Genetic
  • Gene Conversion*
  • Genes, Fungal*
  • Homozygote
  • Kinetics
  • Mitosis*
  • Mutation
  • Saccharomyces cerevisiae / cytology
  • Saccharomyces cerevisiae / genetics*
  • Saccharomyces cerevisiae / radiation effects
  • Ultraviolet Rays