Double-stranded RNAs that encode killer toxins in Saccharomyces cerevisiae: unstable size of M double-stranded RNA and inhibition of M2 replication by M1

Mol Cell Biol. 1984 Sep;4(9):1747-53. doi: 10.1128/mcb.4.9.1747-1753.1984.

Abstract

The sizes of M1 and M2 (but not L) change rapidly with growth, varying by perhaps as much as 33%. Size variation is seen within 76 generations. In addition, the exclusion of M2 by M1 or L-A-E [( EXL]) is mediated by inhibition of replication or segregation, not by enhanced degradation of preexisting molecules.

Publication types

  • Comparative Study

MeSH terms

  • Cell Cycle
  • Genotype
  • Killer Factors, Yeast
  • Molecular Weight
  • Mycotoxins / genetics*
  • Mycotoxins / isolation & purification
  • RNA, Double-Stranded / genetics*
  • RNA, Double-Stranded / isolation & purification
  • Saccharomyces cerevisiae / cytology
  • Saccharomyces cerevisiae / genetics*
  • Saccharomyces cerevisiae Proteins
  • Species Specificity

Substances

  • KHR1 protein, S cerevisiae
  • Killer Factors, Yeast
  • Mycotoxins
  • RNA, Double-Stranded
  • Saccharomyces cerevisiae Proteins