A comparison of neodymium: YAG and argon laser iridotomies

Ophthalmology. 1984 Sep;91(9):1011-6. doi: 10.1016/s0161-6420(84)34199-9.


A prospective short-term clinical study evaluated argon and Q-switched neodymium:YAG laser iridotomies in 40 eyes of 20 patients with primary chronic angle-closure glaucoma. All patients had bilateral iridotomies with one eye randomly assigned to argon laser and the fellow eye to neodymium:YAG laser therapy. In all eyes a patent iridotomy was created in one treatment session. A mean of 12 +/- 11 and 0.033 +/- 0.025 J were needed for iridotomy formation in argon and neodymium:YAG treated eyes respectively. No neodymium:YAG and six (30%) argon iridotomies had marked closure requiring retreatment. Immediate postoperative intraocular pressure elevation greater than 10 mmHg was seen in seven (35%) argon and six (30%) neodymium:YAG-treated eyes. Nine (45%) eyes treated with the neodymium:YAG laser had bleeding from the iridotomy site. No acute lens damage was found in the neodymium:YAG eyes while seven (35%) lenses in the argon group had focal opacities. Seven (35%) neodymium:YAG and five (25%) argon treated eyes had focal nonprogressive corneal opacities above the iridotomy site. Specular microscopy showed a significant central corneal endothelial loss in argon laser treated eyes. No eyes had detectable retinal damage.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Aged
  • Argon
  • Clinical Trials as Topic
  • Cornea / pathology
  • Female
  • Glaucoma, Open-Angle / surgery*
  • Humans
  • Iris / surgery*
  • Laser Therapy*
  • Lasers / adverse effects
  • Male
  • Middle Aged
  • Ocular Hypertension / etiology
  • Prospective Studies
  • Random Allocation
  • Retina / pathology
  • Visual Field Tests


  • Argon