[Blood coagulation changes and pathogenesis of diabetic retinopathy. Recent advances]

Minerva Med. 1984 Oct 27;75(41):2407-20.
[Article in Italian]


In this review the most recent advances in blood coagulation and chronic complications of diabetes mellitus are discussed. Numerous research workers have reported abnormalities in the mechanisms of platelet activation, endothelial cell function, plasma coagulation and fibrinolysis. However, the data available today cannot as yet be interpreted in terms of pathogenesis of retinopathy or any other chronic manifestation of the disease. Consequently, there is at present no rationale for pharmacological prevention or treatment.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Anticoagulants / therapeutic use
  • Blood Coagulation Disorders / complications*
  • Blood Platelets / drug effects
  • Blood Platelets / physiopathology
  • Diabetic Retinopathy / etiology*
  • Diabetic Retinopathy / prevention & control
  • Endothelium / analysis
  • Humans
  • Prostaglandins / blood
  • von Willebrand Factor / analysis


  • Anticoagulants
  • Prostaglandins
  • von Willebrand Factor