Isolation and cultivation of Lyme disease spirochetes

Yale J Biol Med. Jul-Aug 1984;57(4):521-5.


The successful isolation and cultivation of Lyme disease spirochetes traces its lineage to early attempts at cultivating relapsing fever borreliae. Observations on the growth of Lyme disease spirochetes under different in vitro conditions may yield important clues to both the metabolic characteristics of these newly discovered organisms and the pathogenesis of Lyme disease.

MeSH terms

  • Bacteriological Techniques*
  • Culture Media
  • Humans
  • Lyme Disease / microbiology*
  • Spirochaetales / growth & development
  • Spirochaetales / isolation & purification


  • Culture Media