Improved glucose tolerance in gestational diabetic women on a low fat, high unrefined carbohydrate diet

Aust N Z J Obstet Gynaecol. 1984 Aug;24(3):174-7. doi: 10.1111/j.1479-828x.1984.tb01483.x.

Abstract

In a randomized cross-over study 5 gestational diabetic women were tested on a low fat, high unrefined carbohydrate (HC) diet and a low carbohydrate (LC) diet for a period of 4 days each. Glucose tolerance was shown to be significantly improved on the HC diet compared to the LC diet (p less than 0.05). Urinary glucose output was 50% lower on the HC diet (1.3 +/- 1.1 mmol/d) than on the LC diet (2.6 +/- 3.0 mmol/d), although this difference was not statistically significant. Fasting free fatty acid levels were significantly lower on the HC diet (HC 590 +/- 270 mumol/l, LC 690 +/- 270 mumol/l; p less than 0.02); as were the fasting cholesterol levels (HC 5.9 +/- 1.1 mmol/l, LC 6.3 +/- 1.1 mmol/l; p less than 0.01). Fasting plasma glucose, 2 h postprandial plasma glucose, and fasting plasma triglyceride levels did not differ on the 2 diets. These pilot study results suggest that diets low in fat and high in unrefined carbohydrate content are beneficial to the management of women with gestational diabetes.

MeSH terms

  • Blood Glucose / metabolism
  • Cholesterol / blood
  • Diet, Diabetic
  • Dietary Carbohydrates / administration & dosage*
  • Dietary Carbohydrates / metabolism
  • Dietary Fats / administration & dosage*
  • Dietary Fats / metabolism
  • Fasting
  • Fatty Acids, Nonesterified / blood
  • Female
  • Glucose / metabolism*
  • Glucose Tolerance Test
  • Glycosuria / metabolism
  • Humans
  • Insulin / blood
  • Pregnancy
  • Pregnancy in Diabetics / diet therapy
  • Pregnancy in Diabetics / metabolism*
  • Random Allocation
  • Triglycerides / blood

Substances

  • Blood Glucose
  • Dietary Carbohydrates
  • Dietary Fats
  • Fatty Acids, Nonesterified
  • Insulin
  • Triglycerides
  • Cholesterol
  • Glucose