Competition between isogenic mutS and mut+ populations of Escherichia coli K12 in continuously growing cultures

Mol Gen Genet. 1984;198(2):175-6. doi: 10.1007/BF00328719.


Previous studies have shown that the mutT, mutH and mutL mutators of Escherichia coli have a marked advantage in competition growth with otherwise coisogenic wild-type strains. As shown in this paper the same is true for the mutS mismatch mutator. In three experiments mutS could outgrow the wild-type and had higher fitness values.

Publication types

  • Comparative Study

MeSH terms

  • Biological Evolution
  • Cell Division
  • Escherichia coli / genetics*
  • Escherichia coli / growth & development
  • Genes, Bacterial
  • Mutation*