Central venous catheter-induced endocarditis: human correlate of the animal experimental model of endocarditis

Rev Infect Dis. 1984 Nov-Dec;6(6):783-90. doi: 10.1093/clinids/6.6.783.


A case of right-sided endocarditis clearly associated with the presence of a right atrial catheter is presented, and the literature on septicemia and endocarditis associated with central venous and pulmonary artery catheterization is reviewed. In the majority of cases of catheter-associated endocarditis reported in the literature, diagnosis has been made at autopsy; echocardiographic diagnosis has been reported only recently. The case presented in this report represents the only case in this literature in which the lesion causing right-sided endocarditis has been identified by two-dimensional echocardiogram and confirmed by tissue diagnosis. The mechanism of direct traumatization of the endocardium by the catheter makes central venous catheter-induced endocarditis bear pathophysiologic similarity to the experimental model of endocarditis in animals.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Animals
  • Catheterization / adverse effects*
  • Central Venous Pressure
  • Disease Models, Animal
  • Echocardiography
  • Endocarditis, Bacterial / diagnosis
  • Endocarditis, Bacterial / etiology*
  • Female
  • Humans
  • Monitoring, Physiologic / instrumentation
  • Sepsis / etiology
  • Staphylococcal Infections / diagnosis
  • Staphylococcal Infections / etiology*