There is a report given about the effect of Cerutil (Centrophenoxin) at an enteral dosage of 1250 mg/day over a time of eight weeks, applied with 31 patients with references for a cerebral insufficiency conditional on involution. The results concerning the possibility of influencing clinical symptoms, the descriptions of complaints by the patients and the testing methods applied allow the conclusion, that Cerutil can be regarded as a proved remedy, especially at the out-patient treatment of older people with cerebral insufficiency. More serious secondary effects or states of excitement were not watched at the dosage mentioned.