The response to exercise in normal and asthmatic children

J Pediatr. 1978 May;92(5):718-21. doi: 10.1016/s0022-3476(78)80135-8.


Twenty-five normal and 105 asthmatic children were exercised on a treadmill. Pulmonary function was assessed before and after exercise. The maximum fall from the resting value in normal subjects depended on the test used: PEFR 12.5%; FEV1 10%; MMEF 26%; V50 30%; V25 33%. Using these criteria, PEFR and FEV1 detected 99% of those asthmatic children who had a positive exercise response. The largest fall from the resting value was seen with the MMEF, but this test detected only 70% of the positive responders. The pre-exercise function did not affect the severity of the response but did have an effect on the incidence of exercise-induced bronchospasm.

MeSH terms

  • Adolescent
  • Adult
  • Asthma / physiopathology*
  • Child
  • Female
  • Forced Expiratory Volume
  • Humans
  • Lung / physiopathology*
  • Male
  • Maximal Midexpiratory Flow Rate
  • Peak Expiratory Flow Rate
  • Physical Exertion*