CO2 laser radiant heat pulses activate C nociceptors in man

Pflugers Arch. 1983 Oct;399(2):155-6. doi: 10.1007/BF00663913.


Cerebral potentials evoked by noxious CO2 laser stimuli in man have been referred to nociceptive A delta units. This paper shows 1) that ultra short (5 - 50 ms) high power (less than or equal to 50 W) CO2 laser skin stimuli are able to activate nociceptive C units in man, and 2) that these C nociceptors have to be assumed to terminate in the very superficial skin layer (less than or equal to 300 microns depth).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carbon Dioxide*
  • Hot Temperature*
  • Humans
  • Lasers*
  • Nociceptors / physiology*
  • Nociceptors / radiation effects


  • Carbon Dioxide