Benign lymphoepithelial lesion in a patient with Sjögren's disease and an IgG paraprotein

J Oral Pathol. 1983 Dec;12(6):515-26. doi: 10.1111/j.1600-0714.1983.tb00363.x.


Clinical and laboratory investigations were performed on a patient presenting with xerostomia and swelling of the parotid gland. Lymphoid infiltration of the salivary glands (parotid and labial) and paraproteinaemia were found. Immunoperoxidase studies of labial and parotid glands revealed that local immunoglobulin synthesis was essentially polyclonal although monoclonal staining of Russell bodies within the labial tissue suggested that at least some of the serum paraprotein was being synthesised locally. The implications of these findings are discussed in terms of diagnosis and treatment.

Publication types

  • Case Reports

MeSH terms

  • Diagnosis, Differential
  • Female
  • Humans
  • Immunoenzyme Techniques
  • Immunoglobulin G* / analysis
  • Lymphoproliferative Disorders / complications
  • Lymphoproliferative Disorders / pathology
  • Middle Aged
  • Paraproteinemias / complications*
  • Paraproteinemias / immunology
  • Paraproteinemias / pathology
  • Parotid Diseases / complications*
  • Parotid Diseases / immunology
  • Parotid Diseases / pathology
  • Sjogren's Syndrome / complications*
  • Sjogren's Syndrome / pathology


  • Immunoglobulin G