Comparison between human urinary follicle-stimulating hormone and human menopausal gonadotropin treatment in polycystic ovary

Obstet Gynecol. 1984 Jan;63(1):6-11.


Five infertile patients with polycystic ovarian disease were treated to induce ovulation with pure human urinary follicle-stimulating hormone and human menopausal gonadotropin consisting of follicle-stimulating hormone and luteinizing hormone in 1:1 ratio. No substantial differences were seen between the two types of treatment regarding plasma values of follicle-stimulating hormone, prolactin, testosterone, dihydrotestosterone, progesterone, and 17-hydroxyprogesterone. Estrone, estradiol, and androstenedione values were higher during human urinary follicle-stimulating hormone treatments. Luteinizing hormone levels dropped in both treatments, but the fall was greater during human urinary follicle-stimulating hormone. No real differences were observed concerning number of ovulations, length of treatments, and follicle-stimulating hormone amounts administered; no hyperstimulations were observed. These data do not confirm the observation that more controlled responses of the ovaries can be elicited when low luteinizing hormone gonadotropin preparations are used.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Androgens / blood
  • Drug Evaluation
  • Estradiol / blood
  • Estrone / blood
  • Female
  • Humans
  • Luteinizing Hormone / blood
  • Menotropins / therapeutic use*
  • Ovulation Induction
  • Polycystic Ovary Syndrome / drug therapy*
  • Pregnancy
  • Ultrasonography


  • Androgens
  • Estrone
  • Estradiol
  • Menotropins
  • Luteinizing Hormone