Abstract
Genes encoding the T cell alloantigens Tpre, Tthy, Tind, and Tsu have been mapped to a short segment of chromosome 12 using Igh recombinant strains of mice. These loci are located in a tightly linked cluster between the immunoglobulin heavy chain constant region gene cluster, Igh-C, and the serum prealbumin locus Pre-1, in this manner: centromere--Igh-C--(Tthy, Tind)-Tsu-Tpre--Pre-1.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Chromosome Mapping*
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Genetic Linkage
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Immunoglobulin Heavy Chains / genetics*
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Isoantigens / genetics*
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Mice
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Mice, Inbred A
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Mice, Inbred AKR
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Mice, Inbred BALB C
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Mice, Inbred C57BL
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Mice, Inbred CBA
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Mice, Inbred NZB
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Prealbumin / genetics
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Prealbumin / immunology
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Recombination, Genetic
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T-Lymphocytes / immunology*
Substances
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Immunoglobulin Heavy Chains
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Isoantigens
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Prealbumin