Molecular cloning of cDNA for murine interleukin-3

Nature. 1984 Jan 19-25;307(5948):233-7. doi: 10.1038/307233a0.

Abstract

The cDNA sequence for murine interleukin-3, one of the colony stimulating factors that regulate haematopoiesis, codes for a polypeptide of 166 amino acids including a putative signal peptide. The predicted amino acid sequence indicates that formation of mature interleukin-3 involves proteolytic removal of not only the signal peptide but additional amino-terminal amino acids.

MeSH terms

  • Animals
  • Base Sequence
  • Cloning, Molecular
  • DNA / genetics
  • Female
  • Interleukin-3
  • Lymphokines / genetics*
  • Mice
  • Oocytes
  • Plasmids
  • Protein Biosynthesis
  • RNA, Messenger / genetics
  • Xenopus laevis

Substances

  • Interleukin-3
  • Lymphokines
  • RNA, Messenger
  • DNA

Associated data

  • GENBANK/K01850