The beneficial effect of mannitol on postoperative renal function in children undergoing cardiopulmonary bypass surgery

Clin Nephrol. 1984 Mar;21(3):148-51.


A randomized prospective controlled study of prophylactic administration of mannitol 0.5 g/kg body weight in 40 children undergoing cardiopulmonary bypass surgery showed significant lower plasma creatinine concentrations and urinary albumin excretion rates in the treated compared to the control group.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Kidney Injury / prevention & control*
  • Cardiopulmonary Bypass*
  • Child
  • Drug Evaluation
  • Humans
  • Kidney / physiopathology
  • Kidney Function Tests
  • Mannitol / therapeutic use*
  • Postoperative Complications
  • Prospective Studies
  • Random Allocation


  • Mannitol