Binding of Neisseria gonorrhoeae by lectin-like receptors on human phagocytes

J Clin Lab Immunol. 1984 Mar;13(3):107-10.

Abstract

The adherence of gonococci to phagocytes was examined for the presence of "lectin-like" receptors capable of binding these bacteria. The data suggests such "lectin-like" receptors are present on PMN and monocytes that recognize sugars present in the gonococcal cell wall and that there are quantitative and qualitative differences in expression of these receptors. These findings may have importance in investigation of the interaction of gonococci with phagocytes and with the subsequent induction of immunity in the disease.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Binding Sites
  • Carbohydrates / pharmacology
  • Cell Wall / immunology
  • Histocompatibility Antigens Class II / immunology
  • Humans
  • In Vitro Techniques
  • Lectins / immunology
  • Neisseria gonorrhoeae / immunology*
  • Phagocytes / immunology*
  • Receptors, Mitogen / drug effects
  • Receptors, Mitogen / immunology*

Substances

  • Carbohydrates
  • Histocompatibility Antigens Class II
  • Lectins
  • Receptors, Mitogen