The pathophysiology of neurofibromatosis. II. Angiosarcoma as a complication

Cancer Genet Cytogenet. 1984 Jul;12(3):275-80. doi: 10.1016/0165-4608(84)90040-2.


A patient with Von Recklinghausen neurofibromatosis and an angiosarcoma (which developed subsequent to two separate neurofibrosarcomas ) is described, and the association of neurofibromatosis and angiosarcoma is reviewed. The data showed that angiosarcoma is not coincidental with neurofibromatosis, and there is a need to focus investigative efforts on the vascular aspects of this disease.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Hemangiosarcoma / complications*
  • Hemangiosarcoma / pathology
  • Humans
  • Lung Neoplasms / complications*
  • Lung Neoplasms / pathology
  • Male
  • Neurofibromatosis 1 / complications*
  • Neurofibromatosis 1 / pathology