National Survey of Antibiotic Resistance in Pseudomonas Aeruginosa

J Antimicrob Chemother. 1984 Jul;14(1):9-16. doi: 10.1093/jac/14.1.9.

Abstract

The antibiotic susceptibility of 1866 consecutive non-replicate clinical isolates of Pseudomonas aeruginosa from 24 British hospitals was examined. Antibiotics tested and resistance breakpoints selected were: carbenicillin (MIC greater than 128 mg/l), azlocillin (greater than 32 mg/l), cefotaxime (greater than 16 mg/l), cefoperazone (greater than 16 mg/l), ceftazidime (greater than 16 mg/l), amikacin (greater than 4 mg/l) and gentamicin (greater than 2 mg/l). Resistance frequencies detected were: carbenicillin 9.6%, azlocillin 3.9%, cefotaxime 19.0%, cefoperazone 4.3%, ceftazidime 0.3%, amikacin 3.8%, and gentamicin 5.5%.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Carbenicillin / pharmacology
  • Gentamicins / pharmacology
  • Humans
  • Microbial Sensitivity Tests
  • Penicillin Resistance
  • Pseudomonas Infections / microbiology
  • Pseudomonas aeruginosa / drug effects*
  • United Kingdom

Substances

  • Anti-Bacterial Agents
  • Gentamicins
  • Carbenicillin