[Histological and histochemical changes in the hip joint capsule in arthrosis in elderly patients. Study of 57 surgical and 28 autopsy specimens]

Rev Rhum Mal Osteoartic. 1980 Jan;47(1):15-20.
[Article in French]

Abstract

The authors make a histological and histochemical study of the articular capsule, in arthrosis and senescence. They basically observe fibrosis and a decrease of the elastic tissue in aged subjects and an increase in the level of acid mucopolysaccharides of the interstitial in more than 50% of arthrosics. There are also micro-deposits of amyloid substances in more than 25% of subjects over eighty. This study provides an argument in favor of the opinion of Lagier according to which arthrosis should not be considered the same as a manifestation of senescence. On the other hand, it appears that microscopic amyloidose of the articular capsule of the old patient is not related to arthrosic phenomena but rather constitutes a local manifestation of senescence.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Aged
  • Aging
  • Elastic Tissue / pathology
  • Female
  • Glycosaminoglycans
  • Hip Joint / pathology*
  • Histocytochemistry
  • Humans
  • Joint Diseases / metabolism
  • Joint Diseases / pathology*
  • Male

Substances

  • Glycosaminoglycans