Gene dosage effect for glycinamide ribonucleotide synthetase in human fibroblasts trisomic for chromosome 21

Biochem Biophys Res Commun. 1980 Apr 29;93(4):1286-9. doi: 10.1016/0006-291x(80)90629-4.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Alleles
  • Carbon-Nitrogen Ligases*
  • Down Syndrome / enzymology*
  • Down Syndrome / genetics
  • Genes
  • Glycine / analogs & derivatives
  • Glycine / genetics
  • Glycine / metabolism
  • Humans
  • Ligases / genetics*
  • Ligases / metabolism
  • Ribosemonophosphates / genetics
  • Ribosemonophosphates / metabolism

Substances

  • Ribosemonophosphates
  • Ligases
  • Carbon-Nitrogen Ligases
  • phosphoribosylamine-glycine ligase
  • Glycine