[Acute hepatic necrosis and hemorrhagic syndrome leading to a fatal outcome during treatment of hypercalcemia with mithramycin (author's transl)]

Abstract

The onset of hepatic necrosis and a hemorrhagic syndrome, leading to a fatal outcome, was attributed to the toxicity of mithramycin prescribed for an iatrogenic hypercalcemia. This toxicity limits the use of mithramycin for the treatment of hypercalcemias.