the role of autoantibody and immune complexes in the pathogenesis of Guillain-Barré syndrome

Ann Neurol. 1981:9 Suppl:70-9. doi: 10.1002/ana.410090712.

Abstract

Evidence that Guillain-Barré syndrome (GBS) may be caused, at least in part, by antibodies to nerve tissue or soluble immune complexes is reviewed. Although insufficient proof exists at present to confirm a causal relationship between humoral factors and GBS, converging lines of evidence support this possibility.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Autoantibodies / analysis*
  • Demyelinating Diseases / immunology
  • Fluorescent Antibody Technique
  • Humans
  • Immune Complex Diseases / immunology*
  • Nerve Fibers, Myelinated / immunology
  • Peripheral Nerves / immunology
  • Polyradiculoneuropathy / immunology*

Substances

  • Autoantibodies