Bronchodilator effect of inhaled ipratropium bromide in wheezy toddlers

Arch Dis Child. 1981 Sep;56(9):729-32. doi: 10.1136/adc.56.9.729.


Airways obstruction was measured before and after inhaled ipratropium bromide in 32 wheezy children aged between 3 months and 2 years 8 months using a total body plethysmograph and a modification of the forced oscillation technique. No relationship was found between age and incidence of response. About 40% of those under age 18 months had an improvement in lung function. This form of treatment may have a place in the management of the wheezy infant too young to respond to beta-2 stimulants.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Age Factors
  • Atropine Derivatives / therapeutic use*
  • Bronchodilator Agents / therapeutic use*
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Ipratropium / therapeutic use*
  • Male
  • Respiratory Function Tests
  • Respiratory Sounds*


  • Atropine Derivatives
  • Bronchodilator Agents
  • Ipratropium