Topical Deodorized Polysulfides. Broadscope Acne Therapy

Cutis. 1981 Oct;28(4):468-72.

Abstract

True Vleminckx's solution incorporated in a natural clay-mask vehicle apparently retains its therapeutic qualities while relinquishing all unaesthetic properties. A double-blind, randomized clinical trial comparing the Vleminckx mask to its vehicle was conducted. While the mask vehicle may not be considered a placebo, only the active drug produced a statistically significant reduction in comedone count at the conclusion of the study. The Vleminckx mask achieved a substantially greater reduction in papule count than the vehicle (p less than 0.05). Male and female patients responded positively to the concept of every-other-evening applications of only 20 minutes, as well as to the mask's rapidly astringent and cooling skin effects.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Acne Vulgaris / drug therapy*
  • Administration, Topical
  • Adolescent
  • Adult
  • Calcium / administration & dosage
  • Calcium / adverse effects
  • Calcium / therapeutic use*
  • Calcium Compounds*
  • Clinical Trials as Topic
  • Double-Blind Method
  • Female
  • Humans
  • Male
  • Odorants
  • Pharmaceutical Vehicles
  • Sulfides / administration & dosage
  • Sulfides / adverse effects
  • Sulfides / therapeutic use*
  • Thiosulfates / administration & dosage
  • Thiosulfates / adverse effects
  • Thiosulfates / therapeutic use*

Substances

  • Calcium Compounds
  • Pharmaceutical Vehicles
  • Sulfides
  • Thiosulfates
  • calcium sulfide
  • polysulfide
  • Calcium