Ipratropium bromide in children with asthma

Thorax. 1982 Jan;37(1):72-4. doi: 10.1136/thx.37.1.72.


Eighteen children between 6 and 14 years of age with perennial asthma were studied over two four-week treatment periods. Ipratropium bromide, given in addition to their current treatment, was compared with placebo using a double-blind crossover technique. The period of treatment with ipratropium was associated with a significant reduction in symptoms during both day and night and significantly higher morning peak expiratory flow rates.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial

MeSH terms

  • Adolescent
  • Asthma / drug therapy*
  • Atropine Derivatives / therapeutic use*
  • Child
  • Clinical Trials as Topic
  • Double-Blind Method
  • Female
  • Humans
  • Ipratropium / therapeutic use*
  • Male
  • Peak Expiratory Flow Rate


  • Atropine Derivatives
  • Ipratropium