Adenylate cyclase in the Drosophila memory mutant rutabaga displays an altered Ca2+ sensitivity

Neurosci Lett. 1984 Jun 15;47(2):119-24. doi: 10.1016/0304-3940(84)90416-6.

Abstract

Adenylate cyclase in washed, crude membrane fractions prepared from the Drosophila conditioning mutant, rutabaga, displays an altered responsiveness to Ca2+. The results are of interest since the modulation of adenylate cyclase activity by Ca2+ has recently been suggested to play a role in molecular events that underlie memory formation.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adenylyl Cyclase Inhibitors
  • Adenylyl Cyclases / genetics
  • Adenylyl Cyclases / physiology*
  • Animals
  • Calcium / physiology*
  • Chlorpromazine / pharmacology
  • Drosophila / physiology*
  • Memory / physiology*
  • Mutation
  • Trifluoperazine / pharmacology

Substances

  • Adenylyl Cyclase Inhibitors
  • Trifluoperazine
  • Adenylyl Cyclases
  • Calcium
  • Chlorpromazine