The natural history of atherosclerotic and fibrous renal artery disease

Urol Clin North Am. 1984 Aug;11(3):383-92.

Abstract

From 1969 to 1979, 169 patients with two or more renal angiograms for renovascular disease (85 atherosclerotic, 75 fibrous, 9 atherosclerotic and fibrous) were reviewed in an attempt to characterize progression of disease and to determine clinical markers of progression. Progression of renal artery atherosclerosis was observed in 37 patients (44 per cent); progression to complete occlusion was observed in 14 patients (16 per cent). In the 66 patients with medial fibroplasia, progression was observed in 22 patients (33 per cent). Serial serum creatinine measurements in conjunction with measurements of kidney size may be used as markers of progressive atherosclerotic renovascular disease. These clinical markers did not represent progressive disease for individuals with medial fibroplasia.

MeSH terms

  • Adult
  • Aged
  • Arterial Occlusive Diseases / physiopathology*
  • Arteriosclerosis / blood
  • Arteriosclerosis / diagnostic imaging
  • Arteriosclerosis / physiopathology*
  • Blood Pressure
  • Creatinine / blood
  • Female
  • Fibromuscular Dysplasia / blood
  • Fibromuscular Dysplasia / diagnostic imaging
  • Fibromuscular Dysplasia / physiopathology*
  • Humans
  • Hypertension, Renovascular / blood
  • Hypertension, Renovascular / diagnostic imaging
  • Hypertension, Renovascular / physiopathology*
  • Kidney / physiopathology
  • Male
  • Middle Aged
  • Radiography
  • Renal Artery / diagnostic imaging
  • Renal Artery Obstruction / blood
  • Renal Artery Obstruction / diagnostic imaging
  • Renal Artery Obstruction / physiopathology*
  • Time Factors

Substances

  • Creatinine