Characteristics, mortality, and outcome of higher-birth weight infants who require intensive care

Am J Obstet Gynecol. 1984 Aug 15;149(8):875-9. doi: 10.1016/0002-9378(84)90607-0.


The improved outcome of small infants who have received intensive care is well documented; however, the mortality and morbidity of infants weighing greater than or equal to 2500 gm who require intensive care have not been emphasized. During a 2-year period these infants accounted for 41% of admissions and 34% of all deaths in our nursery. The most common diagnoses were pulmonary disease (32%), asphyxia (22%), congenital anomalies (18%), infant of diabetic mother (10%), hematologic disease (9%), and infection (4%). Mortality was 11% with 50% of the deaths from lethal malformations, 26% from asphyxia, 13% from infection, and 11% from miscellaneous causes. One half of the deaths were potentially preventable. According to developmental follow-up, over 90% of the survivors were developing normally. Thus, while outcome for survivors is usually good, mortality remains excessively high. This large and understudied group of infants requires increased investigative emphasis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Birth Weight*
  • Child Development
  • Female
  • Florida
  • Humans
  • Infant
  • Infant Mortality
  • Infant, Newborn
  • Infant, Newborn, Diseases / complications
  • Infant, Newborn, Diseases / mortality*
  • Infant, Newborn, Diseases / therapy*
  • Intensive Care Units, Neonatal*
  • Length of Stay
  • Male
  • Outcome and Process Assessment, Health Care*