Actinic granuloma of the conjunctiva

Arch Ophthalmol. 1984 Aug;102(8):1200-2. doi: 10.1001/archopht.1984.01040030978030.


The key histologic feature of pingueculas is the presence of actinic elastosis of the conjunctival connective-tissue fibers. We describe a patient who had a pinguecula that, on pathologic examination, exhibited a prominent foreign-body giant-cell reaction in association with the elastotic fibers. The term actinic granuloma has been coined recently to designate a similar reaction in sun-damaged skin. Because the nature of the inflammatory reaction may be misinterpreted on pathologic examination as indicating the presence of microorganisms or a foreign body, both the clinician and the pathologist should be aware of this peculiar inflammatory response, which has been described on two previous occasions in patients with pingueculas.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Conjunctival Diseases / etiology
  • Conjunctival Diseases / pathology*
  • Female
  • Granuloma / etiology
  • Granuloma / pathology*
  • Humans
  • Rheumatoid Nodule / pathology
  • Sunlight / adverse effects*