[Pharmacological activity of modified analogs of steroid estrogens. Racemic 8-isoestradiol]

Abstract

The authors have studied pharmacological activity of an estradiol isoanalog-8-isoestradiol. The drug has been shown to possess dissociated hormonal properties. Having a relatively high vaginotropic and antifertile activity, the drug exerts a negligible antigonadotropic effect on the pituitary and a fairly weak uterotropic action.