The intramural pelvic nerves in the colon of dogs

J Physiol. 1984 Sep;354:89-98. doi: 10.1113/jphysiol.1984.sp015364.

Abstract

The intramural pelvic nerves of the dog colon were studied morphologically and electrophysiologically. These nerves emanate from the pelvic plexus, and ascend between the muscle layers along 57.5% of the colon's length. Many thin branches connect with Auerbach's plexus. Most of the nerves responded bilaterally with compound action potentials of A delta and C fibres to stimulation of the sacral dorsal roots, and with those of C fibres to stimulation of the ventral roots. Mean conduction velocities of the A delta and C fibres were 9.0 and 0.9 m/s, respectively. Distension of a section of colon at up to 85.0% of the length of the colon from the anus activated afferent fibres, and electrical stimulation of points at up to 102% of this length elicited responses in efferent fibres. In dogs in which the continuity of the colonic wall was interrupted by a ligature but the nerves were left intact, the intramural pelvic nerves were found to convey centrifugal activities of the recto- and ano-colonic reflexes to the proximal colon, and centripetal and centrifugal activities of the colo-colonic reflex.

MeSH terms

  • Action Potentials
  • Animals
  • Colon / innervation*
  • Colon / ultrastructure
  • Dogs
  • Gastrointestinal Motility
  • Neural Conduction
  • Neurons / ultrastructure
  • Neurons, Afferent / physiology
  • Neurons, Efferent / physiology
  • Pelvis / innervation