Practical toxicologic diagnosis

Mod Vet Pract. 1984 Aug;65(8):589-95.


Strychnine toxicosis is characterized by inducible tetanic seizures and metaldehyde poisoning by fine fasciculations progressing to generalized tremors and seizures. Intoxication with 1080 causes seizures, random running movements, vomiting, defecation, urination, acidosis and hyperglycemia. Intoxication with rodenticides causing coagulopathy is characterized by hemorrhage into body cavities but not necessarily external hemorrhage. Anticholinesterase insecticides cause salivation, urination and defecation, while chlorinated hydrocarbon insecticides cause CNS disturbances. Ethylene glycol intoxication results in ataxia, depression, coma, vomiting and tachypnea, followed by acute renal failure. Urea poisoning causes bloat and CNS signs in cattle. Monensin intoxication in horses lasts several days and causes stiffness, colic, uneasiness and recumbency. Salt poisoning results in depression, seizures and hypernatremia. Lead poisoning is associated with central and peripheral nervous system signs, as well as increased numbers of nucleated RBC and basophilic stippling of RBC. Arsenic poisoning results in GI pain, diarrhea, weakness and death. Copper toxicosis in sheep is manifested by hemolytic anemia, hemoglobinemia and hemoglobinuria. Plants that may intoxicate domestic animals include sorghum, greasewood, halogeton, water hemlock, Japanese yew, larkspur, lupine, milk-weed, philodendron, oleander, castor bean and precatory bean.

MeSH terms

  • Animals
  • Blood Coagulation Disorders / chemically induced
  • Blood Coagulation Disorders / veterinary
  • Central Nervous System Diseases / chemically induced
  • Central Nervous System Diseases / veterinary
  • Ethylene Glycols / poisoning
  • Food Additives / poisoning
  • Insecticides / poisoning
  • Metals / poisoning
  • Plants, Toxic
  • Poisoning / diagnosis
  • Poisoning / veterinary*
  • Rodenticides / poisoning


  • Ethylene Glycols
  • Food Additives
  • Insecticides
  • Metals
  • Rodenticides