Medical complications of infectious mononucleosis

Am Fam Physician. 1984 Nov;30(5):195-9.


Infectious mononucleosis is usually a benign, self-limited disease, but complications may develop in up to 5 percent of patients. The complications can be life-threatening and may precede, follow or coincide with the usual symptoms of infectious mononucleosis. Occasionally, a complication is the only clinical manifestation of the disease. Complications may be due to an autoimmune response, a lymphocytic infiltrative reaction, generalized edema of the airway tissues or enlargement of the spleen.

MeSH terms

  • Adolescent
  • Adult
  • Central Nervous System Diseases / etiology
  • Child
  • Digestive System Diseases / etiology
  • Eye Diseases / etiology
  • Heart Diseases / etiology
  • Hematologic Diseases / etiology
  • Humans
  • Immune System Diseases / etiology
  • Infectious Mononucleosis / complications*
  • Kidney Diseases / etiology
  • Lung Diseases / etiology
  • Lymphoproliferative Disorders / etiology
  • Otorhinolaryngologic Diseases / etiology
  • Skin Diseases / etiology
  • Splenic Rupture / etiology