Functional palatal incompetence in the fetal anticonvulsant syndrome

Arch Dis Child. 1984 Oct;59(10):989-90. doi: 10.1136/adc.59.10.989.

Abstract

We report two children with mild mental retardation and appreciable articulation difficulties whose mothers took phenobarbitone and phenytoin throughout their pregnancies. The speech difficulties in both children were due to malfunction of an anatomically normal palate.

Publication types

  • Case Reports

MeSH terms

  • Abnormalities, Drug-Induced / etiology*
  • Child, Preschool
  • Epilepsy / drug therapy
  • Female
  • Humans
  • Male
  • Maternal-Fetal Exchange
  • Phenobarbital / adverse effects*
  • Phenytoin / adverse effects*
  • Pregnancy
  • Pregnancy Complications / drug therapy
  • Velopharyngeal Insufficiency / chemically induced*
  • Velopharyngeal Insufficiency / congenital

Substances

  • Phenytoin
  • Phenobarbital