Amitriptyline-induced fulminant hepatitis

Digestion. 1984;30(3):179-84. doi: 10.1159/000199103.

Abstract

The authors report the case of a patient who received amitriptyline on 2 occasions. On both occasions, she had fever and jaundice. On the second episode, hepatitis was severe with hepatic encephalopathy, ascites, increased prothrombin time, and massive hepatic necrosis. After interruption of the drug administration, the patient made a slow but complete recovery.

Publication types

  • Case Reports

MeSH terms

  • Amitriptyline / adverse effects*
  • Chemical and Drug Induced Liver Injury / etiology*
  • Chemical and Drug Induced Liver Injury / pathology
  • Chemical and Drug Induced Liver Injury / physiopathology
  • Female
  • Humans
  • Middle Aged

Substances

  • Amitriptyline