Screening for new compounds with antiherpes activity

Antiviral Res. 1984 Oct;4(5):231-44. doi: 10.1016/0166-3542(84)90029-9.


A number of compounds have been tested for antiherpes activity. Actinobolin, amicetin, carrageenan, laspartomycin, megalomycin C, pleuromutilin, suramin and tetracenomycin C showed significant protection of HeLa cell monolayers infected with herpes simplex virus type 1. The action of these new antiherpes compounds was compared with those antiherpes agents that have been described previously. Actinobolin, amicetin and tetracenomycin C were also active against viruses other than herpes simplex.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antiviral Agents*
  • Drug Evaluation, Preclinical
  • Female
  • HeLa Cells
  • Herpes Simplex / drug therapy*
  • Humans
  • Species Specificity


  • Antiviral Agents