Exact confidence intervals following a group sequential test

Biometrics. 1984 Sep;40(3):797-803.


A numerical method is used to compute confidence intervals, which have exact coverage probabilities, for the mean of a normal distribution following a group sequential test. This method, which uses an ordering of the sample space similar to that employed by Siegmund (1978, Biometrika 65, 341-349), is contrasted with the usual confidence interval for the mean.

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Biometry*
  • Clinical Trials as Topic / methods*
  • Humans
  • Probability