Dopamine-containing amacrine cells of rhesus monkey retina parallel rods in spatial distribution

Brain Res. 1984 Nov 19;322(1):1-7. doi: 10.1016/0006-8993(84)91174-0.


Dopamine-containing amacrine cells of rhesus monkey were found everywhere outside of the foveola in whole, flat retinas by the formaldehyde-glutaraldehyde fluorescent method. There were about 7500 such cells in a single retina and their density, determined by cell counts and measured by a nearest neighbor method, was minimal in foveal and peripheral regions and maximal at 3 mm from the center of the fovea. Compared to density distributions of other retinal neuron types, dopamine-containing amacrine cells correlated only with rods, which also had a peak density at 3 mm eccentricity. Cones and ganglion cells peaked in the foveal pit, or within 1 mm of it, respectively. As the distribution of dopamine-containing cells followed that of rods, it is suggested that dopamine could be involved in the rod neuronal circuitry of primates.

MeSH terms

  • Animals
  • Dopamine / metabolism*
  • Female
  • Macaca mulatta
  • Male
  • Microscopy, Fluorescence
  • Photoreceptor Cells / cytology*
  • Retina / cytology*
  • Retina / metabolism


  • Dopamine