Use of cyclosporin A in establishing Epstein-Barr virus-transformed human lymphoblastoid cell lines

In Vitro. 1984 Nov;20(11):856-8. doi: 10.1007/BF02619631.


We have investigated the potential for using cyclosporin A to increase the efficiency with which Epstein-Barr virus-transformed human lymphoblast lines can be prepared. Use of this immunosuppressive drug has permitted the development of a procedure with success rates exceeding 95% despite the processing of very large numbers of samples.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Cell Line
  • Cell Transformation, Viral* / drug effects
  • Cyclosporins / pharmacology*
  • Humans
  • Lymphocytes / drug effects*
  • Lymphocytes / microbiology


  • Cyclosporins