Two cases of death involving dicyclomine in infants. Measurement of therapeutic and toxic concentrations in blood

J Toxicol Clin Toxicol. 1984;22(5):455-62. doi: 10.3109/15563658408992576.


In two deaths of infants investigated by the Medical Examiner, high levels of dicyclomine were detected in blood. In one of the cases, a level of 0.505 micrograms/ml was found, nearly 10 times reported adult therapeutic blood concentrations, and death was ascribed to an overdose of dicyclomine. Gas chromatography/mass spectrometry was used for the analysis of biological specimens.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cyclohexanecarboxylic Acids / adverse effects*
  • Dicyclomine / adverse effects*
  • Dicyclomine / blood
  • Dose-Response Relationship, Drug
  • Female
  • Gas Chromatography-Mass Spectrometry
  • Humans
  • Infant
  • Male


  • Cyclohexanecarboxylic Acids
  • Dicyclomine