Abstract
The venom of female spiders (Aphonopelma seemanni) induces necrosis of skeletal muscle in mice. This effect was demonstrated by histology and by the increase in the plasma levels of the enzyme creatine kinase (CK).
MeSH terms
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Animals
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Arthropod Venoms / toxicity*
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Creatine Kinase / blood*
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Female
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Lethal Dose 50
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Mice
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Muscles / pathology*
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Necrosis
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Spider Venoms / toxicity*
Substances
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Arthropod Venoms
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Spider Venoms
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Creatine Kinase