In 1976 we presented seven patients with anterior uveitis due to leptospirosis with positive serological tests. During the years 1975 to 1977 we had the opportunity to observe a further 16 cases. In most of these cases the serological tests were positive for more than one leptospira serotype--in one case even five. In all the follow-up cases during a period of two to seven months, there was complete recovery. We suggest that leptospirosis is a possibility which should not be overlooked in the diagnosis of anterior uveitis, especially bilateral, in young males working in field irrigation and dairy workers in known endemic areas.