Clinical Trial
doi: 10.1016/s0140-6736(77)91953-5.
Incidence and severity of anaphylactoid reactions to colloid volume substitutes
- PMID: 65572
- DOI: 10.1016/s0140-6736(77)91953-5
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Clinical Trial
Incidence and severity of anaphylactoid reactions to colloid volume substitutes
Lancet.
.
Abstract
All available colloid volume substitutes carry the risk of anaphylactoid reactions. In a multicentre prospective trial, 69 cases of anaphylactoid reactions have been observed among 200 906 infusions of colloid volume substitutes. The frequency of severe reactions (shock, cardiac and/or respiratory arrest) was 0-003% for plasma-protein solutions, 0-006% for hydroxyethyl starch, 0-008% for dextran, and 0-038% for gelatin solutions.
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