In-vitro activity of augmentin against clinically important gram-positive and gram-negative bacteria in comparison with other antibiotics

Zentralbl Bakteriol Mikrobiol Hyg A. 1984 Apr;256(4):523-30. doi: 10.1016/s0174-3031(84)80029-3.

Abstract

The susceptibility to Augmentin of a total of 1,417 bacterial isolates was investigated. Augmentin is a new formulation of the broad-spectrum beta-lactam-antibiotic amoxicillin together with the beta-lactamase-inhibitor clavulanic acid. It was demonstrated that 88% of all isolates tested were sensitive to Augmentin, 9% were resistant. 88% of all Pseudomonas aeruginosa strains fell in the "resistant" category. Only 1/71 anaerobes and 15/286 staphylococci were classified as resistant to Augmentin.

MeSH terms

  • Amoxicillin / therapeutic use*
  • Amoxicillin-Potassium Clavulanate Combination
  • Anti-Bacterial Agents / therapeutic use*
  • Bacterial Infections / drug therapy*
  • Clavulanic Acids / therapeutic use*
  • Drug Combinations / therapeutic use
  • Humans
  • Microbial Sensitivity Tests
  • Penicillin Resistance

Substances

  • Anti-Bacterial Agents
  • Clavulanic Acids
  • Drug Combinations
  • Amoxicillin-Potassium Clavulanate Combination
  • Amoxicillin