Chronic myelogenous leukemia in the dog

J Am Vet Med Assoc. 1983 Sep 15;183(6):686-9.

Abstract

Chronic myelogenous leukemia was diagnosed in 7 dogs. In each case, marked neutrophilia in the absence of infection was observed in association with nonspecific illness. Diagnosis was based on morphologic cytology of blood smears, bone marrow aspirates, and in 1 case, a lymph node biopsy specimen. In 5 cases, treatment with hydroxyurea was successful in lowering circulating WBC counts, but was of questionable value in the prevention of leukemic blast crisis.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Biopsy, Needle
  • Blood Cell Count / veterinary
  • Bone Marrow / pathology
  • Cytodiagnosis / veterinary
  • Dog Diseases / diagnosis*
  • Dog Diseases / drug therapy
  • Dogs
  • Drug Therapy, Combination
  • Female
  • Hydroxyurea / therapeutic use
  • Leukemia, Myeloid / diagnosis
  • Leukemia, Myeloid / drug therapy
  • Leukemia, Myeloid / veterinary*
  • Lymph Nodes / pathology
  • Male
  • Oxymetholone / therapeutic use

Substances

  • Oxymetholone
  • Hydroxyurea