Phase II study of amsacrine gluconate in refractory leukemia

Cancer Treat Rep. 1983 Dec;67(12):1131-2.

Abstract

Twenty-six adults with refractory leukemia were treated with amsacrine gluconate, a new formulation. There were two complete and two partial remissions. This preparation has no apparent advantage when compared with amsacrine lactate.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Aminoacridines / therapeutic use*
  • Amsacrine
  • Drug Evaluation
  • Female
  • Gluconates
  • Humans
  • Lactates
  • Leukemia / drug therapy*
  • Leukemia, Lymphoid / drug therapy
  • Leukemia, Myeloid / drug therapy
  • Leukemia, Myeloid, Acute / drug therapy
  • Male
  • Middle Aged

Substances

  • Aminoacridines
  • Gluconates
  • Lactates
  • Amsacrine