Fluphenazine and multifocal tic disorders

Arch Neurol. 1984 Mar;41(3):271-2. doi: 10.1001/archneur.1984.04050150049015.


In a five-year study, 21 patients with multiple tic disorder intolerant of haloperidol therapy were treated with fluphenazine hydrochloride. Sixteen of these patients had fewer side effects with fluphenazine and had either equivalent (five patients) or better (11 patients) tic control. Fluphenazine can be an effective treatment for multiple tics in patients with dose-limiting side effects related to haloperidol.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Female
  • Fluphenazine / adverse effects
  • Fluphenazine / therapeutic use*
  • Humans
  • Male
  • Middle Aged
  • Tic Disorders / drug therapy*
  • Tourette Syndrome / drug therapy*


  • Fluphenazine