Review of results of four regimens for treatment of chronic non-bacterial prostatitis

Br J Urol. 1983 Oct;55(5):519-21. doi: 10.1111/j.1464-410x.1983.tb03360.x.


Review of the treatment of chronic non-bacterial prostatitis, defined by the presence of more than 500 leucocytes per mm3 in the expressed prostatic secretion (EPS), showed symptomatic response after 3 months of minocycline, trimethoprim, co-trimoxazole or diazepam. Reduction in the EPS cell count was most marked with minocycline, trimethoprim was less effective and poor results were obtained with co-trimoxazole and diazepam. In the absence of established treatment for chronic non-bacterial prostatitis it is suggested that antimicrobial therapy is worth consideration.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Anti-Infective Agents, Urinary / therapeutic use
  • Chronic Disease
  • Diazepam / therapeutic use
  • Drug Combinations / therapeutic use
  • Humans
  • Leukocyte Count
  • Male
  • Minocycline / therapeutic use
  • Prostate / metabolism
  • Prostatitis / drug therapy*
  • Prostatitis / etiology
  • Prostatitis / pathology
  • Sulfamethoxazole / therapeutic use
  • Trimethoprim / therapeutic use
  • Trimethoprim, Sulfamethoxazole Drug Combination


  • Anti-Infective Agents, Urinary
  • Drug Combinations
  • Trimethoprim, Sulfamethoxazole Drug Combination
  • Trimethoprim
  • Minocycline
  • Sulfamethoxazole
  • Diazepam